ReasonItchy SkinAnd Its Enjoyable Nature
Recent studies show that itches are more related to nerve receptors than we think. Itching is a sensation we all know that can be relieved by scratching or gently rubbing the skin. Some annoying itches can be treated with topical ointments, while more severe cases may require oral medications.
Recent studies suggest that some itches are more dependent on the nervous system than we realize. Itches are usually caused by superficial skin lesions; in fact, the central nervous system connected to itchiness is influenced by other neural factors in the body.
The Peripheral and Spinal Nervous System in Feeling Itch
Itch receptors include histaminergic and non-histaminergic receptors that are stimulated by the skin, ultimately leading to the release of neurotransmitters (synapses).
It has recently been discovered that neurotransmitters (synapses) also respond to the spinal nervous system. Itch neuromodulators send messages to the peripheral and central nervous systems by binding to nerve receptors.
The Brain System and Understanding Itch
With the nervous system interpreting itching, the brain activates the action of scratching, providing relief from the itch. Recent studies on itching show involvement of the anterior cingulate cortex in the brain (cingulate and insula), the prefrontal cortex, and even the cerebellum.
As discussed in the health sectionSelMagzThis research has not only explored anatomy but also the connection between the anterior cortex of the brain and the brain’s basal nuclei.
Practical Applications of the Link Between Itch and the Brain
There is a known link between the nervous system and the skin that relates to growth and development stages. However, the details related to this link are still unclear. While identifying sensory structures and metabolism in the peripheral and spinal nervous systems is intriguing, the practical use of this information will greatly aid patients.
This information could be useful in finding better treatment methods for itch, managing pruritus, and addressing severe skin itching that impacts patients’ lives.
In treating atopic dermatitis, which is a common skin disorder, controlling itching is achieved through central mechanisms. The main treatment for continuous itching has primarily focused on side effects experienced by all patients. Identifying neural regions involved in itching can greatly enhance targeted and effective treatment.
